Image-Based PSF File Format

YRT-PET supports image-based point spread function (PSF) input files in two forms:

  • Uniform PSF kernel

  • Spatially variant PSF kernel (PSF Look-Up Table or LUT)

Both formats use standard CSV (comma-separated values) files.

Uniform PSF Kernel

Generation

A utility script is provided to generate uniform PSF kernel files:

yrt-pet/scripts/utils/generate_psf_kernel.py

generate_psf_kernel.py [-h] --fx FX --fy FY --fz FZ --vx VX --vy VY --vz VZ
                       [--size_x SIZE_X] [--size_y SIZE_Y] [--size_z SIZE_Z]
                       -o OUTPUT

Arguments:

  • --fx FX: FWHM (full width at half maximum) in X direction (in mm)

  • --fy FY: FWHM in Y direction

  • --fz FZ: FWHM in Z direction

  • --vx VX, --vy VY, --vz VZ: Voxel sizes in X, Y, and Z (in mm)

  • --size_x SIZE_X, --size_y SIZE_Y, --size_z SIZE_Z: (Optional) Kernel sizes in X, Y, and Z (must be odd)

  • -o OUTPUT, --output OUTPUT: Output CSV file path

Output Format:

The resulting CSV file contains:

1D convolution kernel in X direction
1D convolution kernel in Y direction
1D convolution kernel in Z direction
Kernel sizes in X, Y, and Z directions

This file can be used in YRT-PET reconstruction workflows that support uniform image-based PSF kernels.

Spatially Variant PSF Kernel (PSF LUT)

YRT-PET also supports spatially varying 3D symmetric Gaussian kernels, organized in a structured CSV file (PSF LUT).

Assumptions and Behavior

  1. Symmetry: PSF kernels are symmetric in X, Y, and Z. Distance to the center is treated as absolute.

  2. Regular Grid: PSF kernels are placed on a uniform grid. Each “gap” defines the spacing between kernel locations, and the specified “range” must be divisible by the gap.

  3. Interpolation: Nearest-neighbor interpolation is used to determine which kernel to apply. Out-of-range queries fall back to edge values.

  4. Order: PSF kernels are stored in the order: X → Y → Z.

PSF LUT CSV Format

X,Y,Z range of PSF kernel grid in mm (max offset from center), float
X,Y,Z gap of PSF kernel grid in mm (spacing between kernels), float
X,Y,Z kernel size control (determines how many sigmas are included in kernel), float
SigmaX1,SigmaY1,SigmaZ1  # (kernel at 0,0,0)
SigmaX2,SigmaY2,SigmaZ2  # (kernel at xgap,0,0)
SigmaX3,SigmaY3,SigmaZ3  # (kernel at xgap*2,0,0)
...

Example

For:

  • XYZ range = 50 mm (maximum distance from the scanner center at which spatially varying PSF kernels are sampled in each direction, forming the outer boundary of the PSF LUT grid.)

  • XYZ gap = 50 mm (distance between each kernel center)

  • XYZ kernel size control = 4 (number of standard deviation for the gaussian kernels)

Kernels are located in these positions:

(0,0,0)
(50,0,0)
(0,50,0)
(50,50,0)
(0,0,50)
(50,0,50)
(0,50,50)
(50,50,50)

The file would be structured like this:

50,50,50
50,50,50
4,4,4
sigmaX1,sigmaY1,sigmaZ1
sigmaX2,sigmaY2,sigmaZ2
sigmaX3,sigmaY3,sigmaZ3
sigmaX4,sigmaY4,sigmaZ4
sigmaX5,sigmaY5,sigmaZ5
sigmaX6,sigmaY6,sigmaZ6
sigmaX7,sigmaY7,sigmaZ7
sigmaX8,sigmaY8,sigmaZ8